pentobarbital will minimize the extent or impact of terbinafine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.
pentobarbital will reduce the extent or influence of mifepristone by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch. CYP3A4 inducers haven't been examined, coadministration not recommended by company
Keep track of Intently (1)pentobarbital will minimize the level or outcome of levamlodipine by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital will minimize the level or influence of pioglitazone by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Significance Mysterious.
pentobarbital will reduce the extent or result of lumacaftor/ivacaftor by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.
fentanyl transmucosal and pentobarbital both boost sedation. Stay clear of or Use Alternate Drug. Restrict use to people for whom alternate procedure possibilities are inadequate
pentobarbital will minimize the level or outcome of docetaxel by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Importance Unknown.
pentobarbital will minimize the level or result of quinine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Small/Importance Unknown.
Use an alternate means of contraception or perhaps a backup process when enzyme inducers are employed with mixed hormonal contraceptives (CHCs), and carry on backup contraception for 28 days soon after discontinuing enzyme inducer to make sure contraceptive trustworthiness.
pentobarbital will lessen the level or effect of cobimetinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Steer clear of coadministration. Solid or moderate CYP3A inducers may well minimize cobimetinib systemic exposure by >80% and cut down its efficacy.
pentobarbital will lower the extent or get more info result of ethotoin by influencing hepatic enzyme CYP2C9/10 metabolism. Use Warning/Watch.
pentobarbital will minimize the level or influence of tolterodine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.
Contraindicated (one)pentobarbital will lower the level or effect of lonafarnib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Lonafarnib is usually a delicate CYP3A4 substrate. Coadministration with strong or average CYP3A4 inducers is contraindicated.
Just after stopping a CYP3A4 inducer, as the results on the inducer drop, the fentanyl plasma focus will increase which could maximize or prolong both the therapeutic and adverse results.